Cell Culture Bags – Understanding The Basics

Cell and Gene Therapy Fluid Handling Single Use Systems 3 min read

What do you need to know about Cell Culture Bags? Allow us to provide you with key information and the knowledge you need to make an informed decision on whether they are well suited for your cell application.

The key to producing a successful cell culture is to maintain a sterile environment and handle it correctly to ensure it is free from any form of contamination.

Utilising the benefits found through the use of single-use bags in bioprocessing applications. Adopting bag technology in cell culture applications has proven to reduce contamination risks, improve cell viability and aid flexibility, scalability and monitoring. This can help accelerate delivery to patients.

What are Cell Culture Bags?

Cell culture bags are used to grow, culture and store suspension cells, such as T-Cells. Typically made from a plastic material that is designed to provide an optimal environment for cell growth and protection. The bags can be equipped with a variety of features such as filters, ports, valves and tubing to facilitate the transport and manipulation of the cells within them.

Cell culture bags can be supplied as standard or bespoke design from our manufacturing partners

What are the benefits of using Cell Culture Bags?

Cell culture bags are a versatile and practical tool for growing cells in a laboratory setting. They offer a number of advantages over other types of cell culture vessels, such as flasks or bioreactors.

1. Scalability

Cell culture bags are available in a variety of shapes and sizes which allows for ease of scale up, when you are looking to move from initial research through to larger volume batches further down the line.

2. Reduced Risk of Contamination

Maintaining sterility is crucial in cell applications to prevent contamination and ensure cell viability. Cell bags prevent contamination and provide better control over the quality of the cell product. They do this by creating a closed environment. Closed-environment cell processing helps to maintain the purity of the cells and prevent outside contaminants from affecting the cell culture.

3. Flexibility

Bags are more flexible compared to traditional containers such as flasks or bioreactors. They can be easily integrated into existing closed-system processes through aseptic connections. This allows for additional feeding or withdrawing from the cell culture.

4. Ease of Monitoring

The transparent material of the cell therapy bags allows for visible monitoring and the permeable structure allows oxygen and carbon dioxide to pass through easily. This is necessary for gas exchange during cell processing.

5. Improved Cell Viability

Cell culture bags offer a cost-effective solution for cell processing applications by eliminating the need for cleaning flasks and bottle systems. This not only saves time and resources but improves cell viability and decreases product loss. Leading to higher yields of viable cells.

6. Faster Route To Delivery

The increased efficiency and reduced risk of contamination provided by cell culture bags can also result in a faster route to delivery for patients. This is particularly important in the field of regenerative medicine and cell therapy, where timely delivery of high-quality cells is essential for successful treatment outcomes.

Why choose VueLife® Bag series?

Overall, the use of cell therapy and cell processing bags can provide numerous benefits including cost savings, improved cell viability and faster delivery time to patients.

VueLife Bags for Cell Culture Applications
Saint-Gobain VueLife® Bags for Cell Culture Applications

The VueLife® series of bags offer a highly permeable solution for cell culture and processing applications, the bags provide excellent performance and reliability, ensuring optimal cell growth and productivity.

To learn more about our extensive portfolio of single-use cell therapy process solutions or discuss how we can assist you, please contact us. Our team of experts is ready to help you find the perfect solution for your cell processing requirements.

cell culture cell therapy cell and gene therapy